A Comprehensive Guide to Toxicology in Nonclinical Drug Development

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A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition, is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics and toxicokinetics, formulations, and genetic toxicology testing. It has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

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Pages: 1072, Edition: 3rd ed., Hardcover, Academic Press