This Special Issue focuses on the exploration and development of wild and underutilized plant species as novel horticultural crops capable of enhancing more resilient, diverse, and sustainable agri-food systems. In the context of increasing environmental pressures, climate change, and the growing demand for nutritious and functional foods, these species represent valuable genetic and biochemical resources with strong potential for domestication and cultivation. The Special Issue brings together recent advances in agronomy, plant physiology, food quality, and postharvest science to better understand how wild edible, medicinal, aromatic, and woody species can be successfully integrated into modern horticultural systems. Particular attention is given to their nutritional and phytochemical properties, adaptive traits, and responses to different cultivation strategies.Contributions address major challenges and opportunities related to genotype selection, crop management, product quality, consumer acceptance, and value chain development. By combining experimental studies and comprehensive reviews, this Special Issue highlights both opportunities and constraints associated with the transition.
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