The Science of Ebola

Connecting minds with knowledge. With its acclaimed authors, cutting-edge content, emphasis on medical relevance, and coverage based on landmark research, The Science of Ebola has earned an impeccable reputation as an authoritative and exciting curated research journal and learning aid, perfect for students, medical professionals and other sophisticated readers. Hundreds of hours were spent compiling and editing this volume such that its readers are conveniently brought up-to-speed on the subject, presenting many of the latest and most important developments in the field. This volume presents 20 cutting-edge research papers on ebola, curated by our experts for maximal significance. Articles include: Transmission dynamics and control of Ebola virus disease (EVD): a review; Ebola, epidemics, and ethics - what we have learned; Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga; Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries; Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry; Impact on nurses of ebola outbreak; Guidance for contact tracing of cases of Lassa fever, Ebola or Marburg haemorrhagic fever on an airplane: results of a European expert consultation; “A time of fear”: local, national, and international responses to a large Ebola outbreak in Uganda; Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins; Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain; Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned; Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies; Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum; A bioengineering approach for rational vaccine design towards the Ebola Virus; Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus; Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology; Packaging of actin into Ebola virus VLPs; and Ebola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cells.