Surgery for digestive neuroendocrine neoplasia

Surgery, the only curative treatment for well-differentiated localized neuroendocrine tumors, plays a major role in therapeutic strategy. It also has a place in metastatic forms. Whenever possible, surgery for liver metastases is recommended. This excision must be as complete as possible, at an acceptable operative risk. It must be supported by other complementary techniques:Preoperative embolization, radiofrequency. Two-stage hepatectomies can treat all metastases.Hormone therapy with somatostatin analogues is of great importance for symptom control; particular caution must be exercised both before and during surgery. A multidisciplinary approach is essential to provide personalized therapy for patients with NNE. Clinical research and specialization in this field should be further encouraged.