Stem cells have revolutionized regenerative dentistry by offering innovative approaches for the repair, regeneration, and replacement of damaged oral and craniofacial tissues. In pediatric dentistry, stem cells derived from dental tissues possess remarkable regenerative potential and hold promise for vital pulp therapy, dentin-pulp complex regeneration, periodontal tissue engineering, craniofacial reconstruction, and bioengineered tooth regeneration.This library dissertation reviews the biological basis of stem cells, their sources, properties, current clinical applications, recent advances, limitations, ethical considerations, and future prospects. By exploring contemporary evidence, it highlights the transformative role of stem cell-based therapies in advancing minimally invasive and regenerative approaches, paving the way toward personalized and biologically driven pediatric dental care.
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