Mathematics and Visualization Computational Diffusion MRI

This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI’18), which was held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention in Granada, Spain on September 20, 2018. This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI’18), which was held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention in Granada, Spain on September 20, 2018. It presents the latest developments in the highly active and rapidly growing field of diffusion MRI. The reader will find papers on a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as harmonisation and frontline applications in research and clinical practice. The respective papers constitute invited works from high-profile researchers with a specific focus on three topics that are now gaining momentum within the diffusion MRI community: i) machine learning for diffusion MRI; ii) diffusion MRI outside the brain (e.g. in the placenta); and iii) diffusion MRI for multimodal imaging. The book shares new perspectives on the latest research challenges for those currently working in the field, but also offers a valuable starting point for anyone interested in learning computational techniques in diffusion MRI. It includes rigorous mathematical derivations, a wealth of full-colour visualisations, and clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics alike. This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI’18), which was held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention in Granada, Spain on September 20, 2018. It presents the latest developments in the highly active and rapidly growing field of diffusion MRI. The reader will find papers on a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as harmonisation and frontline applications in research and clinical practice. The respective papers constitute invited works from high-profile researchers with a specific focus on three topics that are now gaining momentum within the diffusion MRI community: i) machine learning for diffusion MRI; ii) diffusion MRI outside the brain (e.g. in the placenta); and iii) diffusion MRI for multimodal imaging. The book shares new perspectives on the latest research challenges for those currently working in the field, but also offers a valuable starting point for anyone interested in learning computational techniques in diffusion MRI. It includes rigorous mathematical derivations, a wealth of full-colour visualisations, and clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics alike.

These Proceedings of the 2015 MICCAI Workshop “Computational Diffusion MRI” offer a snapshot of the current state of the art on a broad range of topics within the highly active and growing field of diffusion MRI. The topics vary from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms, new computational methods applied to diffusion magnetic resonance imaging data, and applications in neuroscientific studies and clinical practice. Over the last decade interest in diffusion MRI has exploded. The technique provides unique insights into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into clinical practice. New processing methods are essential for addressing issues at each stage of the diffusion MRI pipeline: acquisition, reconstruction, modeling and model fitting, image processing, fiber tracking, connectivity mapping, visualization, group studies and inference. This volume, which includes both careful mathematical derivations and a wealth of rich, full-color visualizations and biologically or clinically relevant results, offers a valuable starting point for anyone interested in learning about computational diffusion MRI and mathematical methods for mapping brain connectivity, as well as new perspectives and insights on current research challenges for those currently working in the field. It will be of interest to researchers and practitioners in the fields of computer science, MR physics, and applied mathematics.