Intercellular Adhesion Molecule 1 in Health and Disease

Intercellular Adhesion Molecule 1 in Health and Disease provides a comprehensive and up-to-date overview of ICAM-1, one of the most extensively studied adhesion molecules in immunology and vascular biology. The book explores its molecular structure, gene regulation, signaling pathways, and physiological functions before examining its central roles in immune surveillance, inflammation, infection, tissue repair, cardiovascular and neurological disorders, and cancer. It also discusses ICAM-1 as a diagnostic and prognostic biomarker, its therapeutic targeting through antibodies, RNA-based approaches, nanotechnology, and targeted drug delivery, and its emerging applications in immunotherapy and precision medicine. Integrating recent advances in molecular biology, multi-omics technologies, artificial intelligence, and translational research, this volume bridges fundamental science with clinical applications. Written for researchers, clinicians, graduate students, and biomedical professionals, it serves as a single authoritative reference on the biology and clinical significance of ICAM-1.