Implementation Science, Scaling and Sustainability

Why do effective interventions so often fail to produce the expected benefits in real-world settings?Implementation Science, Scaling and Sustainability examines how evidence-based interventions are adopted, adapted, delivered, evaluated, scaled, and sustained across complex health systems.The volume introduces major frameworks including CFIR, RE-AIM, and PRISM, while addressing implementation strategies, fidelity and adaptation, organizational readiness, capacity building, formative evaluation, continuous improvement, dissemination, scale-up, and long-term sustainment. It also considers pragmatic and hybrid study designs, stakeholder engagement, implementation in resource-constrained settings, and the relationship between implementation, service performance, health outcomes, equity, and cost.Throughout, the book distinguishes intervention effectiveness from implementation success and emphasizes context, measurable outcomes, adaptation, and learning over time.Written for advanced students, researchers, health professionals, managers, and policymakers, it provides a structured framework for translating evidence into sustainable practice.