Experimental Medicinal Chemistry-III: B.PHARM

Medicinal Chemistry Lab is a core practical subject in B.Pharmacy where you apply the principles of organic chemistry to make and study drugs. It bridges the gap between theoretical drug design and actual synthesis of medicines. Synthesis: Prepare simple drugs and drug intermediates using standard organic reactions. Purification: Learn recrystallization, distillation, TLC, and column chromatography to get pure compounds.Characterisation: Confirm identity and purity using melting point, TLC, UV, and IR spectroscopy. SAR understanding: See how small structural changes affect physical properties and biological activity.Green chemistry: Use safer solvents, microwave synthesis, and reduce waste.Safety & Documentation: Follow GLP, handle toxic chemicals safely, and maintain proper lab records.Lab techniques you'll use: Reflux - For slow organic reactions, recrystallisation - Purification using ethanol, water, TLC - Monitor reaction progress, check purity. Common solvent: Chloroform: Methanol 9:1. Melting point - Check purity. Pure compound = sharp MP Column chromatography - Separate closely related compounds.

Pages: 64, Paperback, LAP Lambert Academic Publishing