Evidence Base of Clinical Diagnosis

Provides a useful framework for clinical researchers, showing how to choose appropriate study designs and to prepare and execute diagnostic studies effectively. This edition includes new chapters covering the STARD guidelines (Standards for Reporting on Accuracy Research on Diagnosis) and the analysis of diagnostic data. This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available. This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.

While most books on evidence-based medicine deal with the interpretation of diagnostic test results, 'The Evidence Base of Clinical Diagnosis' addresses methods to construct the design itself. The book presents a framework for choosing an appropriate study design, and for preparing and executing diagnostic studies. Guidelines for both original empirical studies and systematic reviews are provided, and the applicability of research results are addressed. In addition, the book covers clinical problem solving, diagnostic decision support using ICT, and implementation issues.