Electrospun Nanostructures in Drug Delivery

This book embodies an interdisciplinary merger of cutting-edge techniques (multiple-fluid electrospinning), advanced architectures (core–sheath, Janus, and their combinations), and broad applications in drug delivery. The 11 chapters progress from simple processes and structures to increasingly sophisticated ones. This book embodies an interdisciplinary merger of cutting-edge techniques (multiple-fluid electrospinning), advanced architectures (core–sheath, Janus, and their combinations), and broad applications in drug delivery. The 11 chapters progress from simple processes and structures to increasingly sophisticated ones. After a concise introduction to the relevant concepts, the book successively reviews electrospun-nanofiber-based drug delivery systems (DDSs) prepared from single-fluid blending, coaxial, side-by-side, and triaxial electrospinning; tri-layer Janus nanofibers; core–sheath/Janus hybrids; beads-on-string structures; layer-by-layer fibrous mats; and composites that couple nanofibers with products derived from other techniques. For the first time, systematic links between these complex electrospun nanostructures and their DDS performances are drawn. A series of novel tri-chamber nanostructures is also examined. In addition, the book offers concrete recommendations for accelerating the industrial translation of nano-DDSs and discusses future societal-level collaborations that could drive the field forward.