Bioinformatics: foundations, methods and applications

Bioinformatics is a discipline born of the convergence of biology, computer science and information processing. The aim of this book, entitled Bioinformatics: foundations, methods and applications, is to present the central role of computer science in the analysis, management and exploitation of biological data. It is aimed at students and teacher-researchers, and assumes mastery of basic notions of statistics and IT tools. The book deals with the integration of biological data of various origins for the modeling of living systems, with the aim of understanding and predicting their behavior in normal or pathological conditions. It covers sequence banks and databases, sequence alignment, and methods of analysis, prediction and comparison. Examples of bioinformatics software are also presented to illustrate the concepts covered and facilitate their application in research work.