Advances in Pharmaceutical Biotechnology

Discusses uses of novel technologies for production, formulation, and synthesis of biological substances from living organisms. Covers specialized areas in pharmaceutical technology, including biotherapeutics, principals and science of vaccinology, bioprocess and fermentation technology, therapies like gene therapy etc. This comprehensive new two-volume work provides detailed explanations of the procedures involved in the development and manufacture of biopharmaceuticals as well as the uses and applications in healthcare and medicine. Volume 1 offers an introduction and overview of pharmaceutical technology, covering the principals and science of biotechnology. It explains genetic engineering that involves laboratory-based technologies to alter the DNA makeup of an organism; protein engineering to develop valuable proteins through the design and production of unnatural polypeptides; recombinant DNA technology to manipulate and isolate DNA segments of interest; and microbial biotransformation, which transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions.